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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b1fc4bdb88674d78d2380caf053e7236f99f838a1640e6e5e612dd99ca3eb21' 
  AND token = '9qQNO/o6S9bTHoCwZxracoZ7fF4xGQKTEmD9+XVqUis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}