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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55749942c9a9d52dcdd1a9c74bf359a10d710222d3e12b7f13260e6ae26bad16' 
  AND token = 'v9N2dsTjGEMCEOhbtPY2b9+5PujQtTjc3zymMaWeCnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}