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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3da5e4aabe266c7e597cfc6e145511658ae8011e2903e295076711d3f60fee4' 
  AND token = 'zqTY3E0bg+hiPsy1G2/5TO2OSkZqEuCuCrWACGJxIAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}