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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e342e2e9cc88f40068b7371ed4871227888fb40d3a645b81d304cb459b6b83f0' 
  AND token = 'dd/lgCXu6Uo6jwvOxK/kwprA0RRdbfSKokUqlYlMhts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}