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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a0c15367314cedc9a4aa5678014b41000713863ef052a757a7bf54640fa7a15' 
  AND token = 'pqlsz7ke8bnKHF/H+2qQKwLl6s7Dyga34GCAyeGro7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}