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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2da266e6195081510b5f7ea58783dc894e117e3e4b7ca534f8c544e0589ae6e' 
  AND token = 'W1iFEO5Kaqs+fXQVGWpMkS8fpKsX4MoeRkhJVz8MGmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}