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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aeb5f973ba7d8c27c12086a5cd333fb5376b8558b3c5034af2a3b2a1c20c221' 
  AND token = 'Na74+3K8et6z6nOuT32GxoWVlHgH0QrOZgOJlQ4PC6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}