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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4d8b4e23a706087ce561023a82b8bd6006a2a2b27af58bf1ff6d4bedbe98feb' 
  AND token = 'E1pFQukqOfn2lZjUg6MXE60qK8xwbz1aC1sbUHHe9hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}