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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53643621ee177b97e9fa8fddc8326ee36c3fcfa2fc529b0b650c8104062c70ae' 
  AND token = 'gbzsNVNgLMTC6yzpAgnp6ooB2i5ELTe9TAZEc/AzAtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}