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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25221109bee4e8d60469445bb94f19cf0a4e995ec654e467546d0d9d09ef181f' 
  AND token = 'e+YIe4gYjvWQy9ChNmcb5RnUUS/vEEguYRAwbH0h69g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}