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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60c4c1bc69212aff65888623fe8390e1e9f7cc36ea05c2b54083577b53ad2922' 
  AND token = '8RPw7Y7+V3C6QlPJoj23++0Rwk4NkM0WKqXN28ObLgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}