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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c51640077bf58bc0b4beaccc104deeabb4f748ad2268875d645a9d2e336b23c3' 
  AND token = 'y2Bjy/T7kh6DHZwkju3G+YqSfcN6rqlm4FwIz3lp3H4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}