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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c190bacab1c5cc937d9e9f81f929ec99b09adb624c20bea59b96b39388b70a' 
  AND token = 't3eIMK7RL4fEbytVg46iBHWMP6kY0n1GtrLvxB6GYUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}