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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3a6ad7456c92083b5f5ee409e3586291803605bf206d92110dbac95711f988b' 
  AND token = 'GKHgmPMO4AfNVgMpguuhFRX/IhBagPMUWtp52ugl30g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}