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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f2daf225fb7783b4ada63c061feb66981f5589549d7b37230579df4c6e5ffb' 
  AND token = '+5cqRxBm8ekKkZoGc2ew/AIMTDm6e2zrwe1DfjataV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}