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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dddfc47f1b116271b4e49c72385320df64e79625c8d0b50ad250dda05722544' 
  AND token = 'rMQ0dM5DZqPAXPcNH0MRU9LWcNw3iXQ5Xto2+jbcpv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}