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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ad2f51912fe8ca1be2b218e2d5ceb276d512b8ad56f3132ba8adeb9cd3d647' 
  AND token = 'tXaS2voPnY1Y2J8hQJrgyRSXkCpMLgH1VBb2aadkBRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}