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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '002eb2ad5ea19cdc52e6f222d14a4ce5fe860602f28544a813084e7c5aa279cf' 
  AND token = 'gvRb5O0YgcrpL10mPt9cNbQ0dWJlN1LvjJChwM1kzNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}