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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d16e6e1ee0ff8b25e364ea4788774d48af9b38eb53bc2baad44d5ff4023355' 
  AND token = 'SI4Tddh8gBv6Nq4XlrDEVCgBM6U0F+IG5FJAzq3rJzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}