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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '954acf7850df275e71086c5908a19f30b9663ce3a025c6c4958e31bb3e2d2244' 
  AND token = 'BnxEyn8spTTDOCG0ca1tCDYCEiTpynhbzWrAmVfYOGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}