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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcfc56539a73abc5aa3a0274c2f899464ca28755da6499ed573b2348c9d04533' 
  AND token = 'PiqqrDjN1zP7Dn8i8dkCeObdtQJ+Id9oDroB20JMh+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}