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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e49b11deccb403a8e1501d2c67ca3713b5d6573aa09e0d415e2d632428a7643' 
  AND token = 'UoSs09BOhgZjW6AjmEKsOI0E0Kq0mvvgr4LMzJIQdl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}