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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80134312a405c4894f22ac05f0d8874cdc79f8fe080776da4f034f550ed4947a' 
  AND token = 'sxgBL50788Kg/70CM/nUbz0riqLwenAA1ZJ0qb5cZWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}