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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3788f94b567033f33e169f22781ecdefd60bc3cc63a17f326fb38251aa1e02ef' 
  AND token = 'HUAe6xiQV67LoVdx4CYH/lMgYg4S3yMWuziMf3U6QpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}