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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fa7d459da67d9355d5d8076f7c9df5cc51b58ad24df649a545923f305e41158' 
  AND token = 'PxwjCxA7HqTyL4s7iyMiUNtYJqc0QLwxLwBzUyDy0rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}