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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5d616bdc5db17880711ded47702983ca96593b13994c138db55833c67abd1da' 
  AND token = 'HzmwB3uhooT3RgzEXKu79IoKPsuRfC+ybG+3W5394Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}