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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6886703699b1d135bdb3c46b6819792944ab231de2867b77d8941dd58088bbbb' 
  AND token = 'B/GNoiySE+Zvx4B83ttCtp8Hnt8GJhswnkGVx3bBgPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}