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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e7b19e3e05a170cb089a8d756d3f87644f79b04da9364a03d11bdc31496d5e9' 
  AND token = '4tQEWdhA7a+wRxyxfXOa5lLqdnoDNSk0LCV1K2PHrOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}