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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1459ccce9aed4846cc346682459a82ced93aa13dd1e3d21005f682535da63393' 
  AND token = 'sMw+Ht26AtBjMYuSsstUxX0AkjKLg/Myssk9Pw75pR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}