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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a4753d8c952fe90af14ed8192d9b112be0d5cd2068f222ccb5f4a9065858c25' 
  AND token = 'xD3fVq4nERMtpknv8PBn8KSG4atFaD/6dqHbIpW53MU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}