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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b1d5259aace0c116d1617b3245ef6520730d19ed1a78852e0d589ac71d995c8' 
  AND token = 'UBw2NY+Pc5olf6aIlY+7zNJEHzOSVzp5zA7PZU8vFQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}