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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f16503c7daccac9f367737e16dbf37e45f4f01cf14e18655326927229938cfd0' 
  AND token = '7jZj7aYUesfJV9PGb/n1i7NIR6TaGy4zmGiJ2XrQr5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}