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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c67158a49daebe4c406ff7f7ee082cdf453547fc365d8ffe02c7b2c3a361e656' 
  AND token = 'PsyZ6o1co2WgD1nHLJo3icXJrBCUMOOMPrAEx1/XBGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}