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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18c4c112ff545dc1c746cd5cbdcecdd1e275b8d7bdd4e2b85602de3409d93e00' 
  AND token = 'd1+9qyX5xxgDva2gmrxwTx+d7HpqM5VPDtzECZmHoGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}