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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca491bc6caeb984f59ff3b59e5f9114fc1e9af091059f5daee1164639f1a2e52' 
  AND token = 'yL4YhZkcKanQgmLM2ENzojA8fx6nND+CouwcJhW5wXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}