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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a346a22117793492a4c914bce1a6e3a55d83529ebe26d40378d063d7b9f273' 
  AND token = 'l7e23YudbiwmtSVHhvIveVntY4NYNp5J1FitAPAnlMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}