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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18810ebd413c7a4b8928560f06b42cac2bf91e81ba4387e580634ff5dd98f2bf' 
  AND token = 'RQqMkRH5+sHY2Rd5Vpof7/QKOUJI+0RFOUSgKEtMipY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}