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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4f4e72cc04290e313abe27e438397fee770ae04281f9332fbbcc431e212039d' 
  AND token = 'FzD1IOSMLpDfmeOgRHFsRW7YA8DEdMiFJ1OY/M6Q0D0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}