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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dab46d8e9a48b06687d9f9f2e6517ad93ab4c974be5b3af9de5a721a89b933aa' 
  AND token = 'Yx6F1bHm6EGDbx4uB5HSLpafFEuEIqD+tTslFQHqfgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}