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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ce7141b4cdf373907f3e6beeee6b365484e3f449da50f2736d4fd018b27ec6d' 
  AND token = '1Gzs+Lww3efzr7kPb8MS32XZNaPqoPkVv/Q4ZRcQK9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}