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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06727cf286f2376e1bf1275aa3c9d6881350bab63e1c3bb3d203c779d70556d7' 
  AND token = 'ksm7HTtOR9LTRCoyI2OT1zAkJphC5OfGst6Vsw78VCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}