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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b0c93a75d850e9b95f2948c2fbbe5c9a6f784cfdd50b43dca05de9a5a99a7f6' 
  AND token = 'az2bICFND/27VsWfvd11vGWEQdJkEw/lCqy6KtMmfk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}