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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10739d3c923c398e7f5b501c0a01876615c11b0efe672aa81990150915db04f9' 
  AND token = 'ND84hx17yanjcxAKmLMX2wrG0+zhKyu+eBpv77BdR44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}