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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e204d3df517c0c3ce9724f7902dbf6c5ac5586afd0235f4da7271c5b68e0e25' 
  AND token = '+3+Nqw2CWiIWjZ9gKD2RIETWBje6jZKDWs05+h0j5jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}