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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5817da3c95737fc43970f1833486e88a0364592a28c4754a3b2904e87f92445' 
  AND token = 'hqtxyi41Pw/f20ASYMujefekdkpSFtv5GkzYjSb4o7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}