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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9c3368ffba42d787ee7f22d43fa86873bc9d9715414aec6b3639daab6f9c624' 
  AND token = 'r9Hsb4AJcjvfXaSo0xFHkfd1zviYjMFt6EPnqCyCdGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}