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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '517c67737e4d9b168fc5aaf435ecc78cc3a58c905c0a19d6b341a2542e43b065' 
  AND token = '5zA7XoF6aF8DPZvHCwYgY6jgAb33fEcf7gC1NXJknYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}