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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4a3f0a2108dcdc1cd7a09798ce54ef0ad01f5528067819f75336374aef0d358' 
  AND token = 'pyf0kNpdXKqoJhkI++tnYyPoGwizxsckpwK3MTLZkv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}