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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb922d11c8d9890096c64b79e6b83aae25219815f066a14630c2d05713fdff05' 
  AND token = 'TbYrjza2dH6QHsBw+4YH3/UAH8FZXvW215ykZgiBWk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}