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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16951f6ce5cc0296d47d9aa37e622fa626fa0b7a79fc4698ded806d5be2daa4b' 
  AND token = 'ig4I1fBOgV52kbbHFjjXcta2mUFNuzdW5y0jQeZLQkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}